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That is hard to say because the weather effects everyone differently. I know when it is cold outside, living in south central Texas, (it doesn't happen but a couple times a year), the heat comes on and makes it dry inside. This effects my breathing and I use a humidifier. I kept it set at 45% humidity and this seems to help me a lot. I have also noticed, for me anyways, that when the barometric pressure drops, I also have some breathing problems. Since I cannot change the barometric pressure, I use my albuterol more often during these times. Have you talked with your medical provider about this? They should also be able to help with more suggestions since they know your medical history. Sorry I couldn't be of more help. Take care and God Bless!