I started on Albuterol .083%/3ml solution every 4 hours as needed about 6 months ago. I'm currently using it every 4 hours around the clock, which means being woken up throughout the night by shortness of breath... and doing another treatment. On particularly bad days, my SOB starts kicking in after 3 hours... at which point I do 1 puff of Ventolin to get me through to my next treatment. Of course if it gets really bad, I'll just do a treatment early.
I've discussed this with both my pulmonary and pcp doctors and their response has been... do what you need to do. Which to me means, a) use the drugs I have to get relief, b) suffer through sob till my next scheduled treatment or c) 911 to the ER... where they will hit me with a massive dose of steroids and back to back duoneb treatments with an external vent on standby.
Check with your doctors, if you haven't already..... and good luck.