Rejuven Air liquid nitrogen spray trials
Is anyone familiar with the RejuvenAir liquid nitrogen trials to treat chronic bronchitis? My pulmo is wanting me to test to see if I qualify for the procedure. So far I would be the first to have the procedure here if I qualify. I can't find any results of any prior procedures anywhere. Very skeptical of being the first test rat.
Hi Greg, and thanks for this post.
I am not familiar with this type of therapy or the clinical trials that may be associated with it. I was able to perform a quick search to see what is out there for you to read.
I thought you might find it helpful in making a decision to look over this article: https://clinicaltrials.gov/ct2/show/NCT03893370.
What do you think?
Leon (site moderator COPD.net)Thank you for your reply Leon. You can go to rejuvenair.com for more information about their trial for treating chronic bronchitis. Basically, they insert a scope down your bronchial and spray liquid nitrogen.
Chronic Bronchitis patients, the airways have been damaged. Cilia, tiny hair-like cells lining the lungs that help move mucus and debris out of the airway become dysfunctional, inducing an overabundance of goblet cells which over produce mucus. The combination of these factors contributes to inflammation, which makes it difficult to breathe.
The RejuvenAir System delivers small, metered doses of cryogen spray which flash freeze the surface area of damaged airways. Diseased cells are destroyed, leaving behind the extra-cellular structure that allows for new healthy cells, including cilia and mucus-producing goblet cells, to repopulate.
Hi Greg, and thanks for replying and for your further explanation. I appreciate you directing me towards the 'rejuvenair' site. I had read the narrative and find it the same as what you've explained above.
I am hopeful this type of new therapy will be effective. My concerns are the same as all concerns for clinical trials in general.
You may want to discuss this at length, and in detail, with your physician and even the company clinical representative. Only then can you make the decision (in collaboration) with your physician. You may want to address issues such as expected levels of improvement, side effects, adverse effects, how long it takes for new cells to regenerate/repopulate.
There is no question this could be extremely exciting!
What do you think, Greg?
Leon (site moderator COPD.net)
My deciding factor in not participating in the trial, after throughly reading the contract and in my interpretation of same, is the sponsor will not cover any costs for other surgical treatment(s) that might be necessary from the result of the trial procedure itself i.e. punctured lung etc.
It does state that 67 people have had the procedure but the findings have not been released.
I would be willing to participate in the trial at this stage of my copd if not for the possible financial risk associated with it.
Since the procedure has been approved in Europe, those results should be available somewhere but I can't find them.
I've been told that numerous hospitals throughout the country are participating in this trial. I'm surprised more copd patients are not aware of it. I'm looking forward to hearing more about it.
Hi again, Greg, and thanks for your most recent response and more information. The choice, naturally, is completely up to you. From my own personal / professional perspective, I agree with your decision.
I, too, am looking forward to hearing more about this procedure/treatment as it reads well and sounds promising.
We will just have to wait and see!
Warmly,
Leon (site moderator COPD.net)
