Hi derick and thanks for your inquiry. The medication in spiriva is a long acting muscarinic agent (LAMA) called tiotropium bromide.
The DuoNeb inhaler combines two medications: Ipratropium bromide and Albuterol.
The medications are somewhat different and you can see the Spiriva has but one medication while the DuoNeb combines two.
This brief answer is meant to be but a very general response to your inquiry. You may want to look further (on our website and/or the internet) for more detail. What exactly are you looking to learn about these medications?
Leon (site moderator)