Hi KaisNana and thanks for your post. I'd be curious if you could locate the literature you seem to have read on the interaction between Spiriva and caffeine. I do not recall seeing any kind of conflict between the two. A brief search of the literature revealed nothing as well. You may want to discuss this further with your own physician; specifically, if YOU need to avoid caffeine or, if there is some contraindication for you to using Spiriva and caffeinated products. Please be sure to check back with us and let us know how you're doing. All the best, Leon (site moderator)