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I have not had that problem because I haven't had any heart problems to date. But I find it hard to believe that your medical team cannot find an inhaler/ heart medication combo that works well for you in both areas. In this day and age, with all the different medications, the odds are there is a combo that does not interact with each other. I would talk to my medical providers and find a solution. Let the forum know what happens. Take care and God Bless.