Human clinical trials are an expensive component of the drug discovery pathway, which often fail due to the fundamental differences between humans and animal model physiology.
But now with organoids, scientists can screen multiple therapies at once, streamlining that process and helping to reduce the number of animals used for research. New compounds or combinations of drugs can be tested on human organoids earlier, discarding unsafe, ineffective or toxic drugs immediately. In turn this helps speed up new drug discoveries and reduce the overall costs of medicines.
As organoids are similar to original organs, scientists use them to study organ development and diseases. These mini-organs can be stored in biobanks and can be used for scientific research, drug screening, disease modeling, precision medicine and regenerative medicine.