I’ve had COPD for many years and take Ventolin, Symbicort, Prednisone, Azithromicin, DuoNeb, Spiriva Respimat and now have been put on oxygen. Nothing lasts like it should. I am still trying to quit smoking. I retired this year because I kept getting coughing attacks at work. I’m embarrassed to use the oxygen and only use it at night, occasionally. I’m tired. All the time.