Utibron™ Neohaler® (indacaterol and glycopyrrolate)

Utibron Neohaler is an inhaled medicine used to treat chronic obstructive pulmonary disease (COPD). Utibron Neohaler contains a combination of medicines that are used as a maintenance therapy to relax the muscles in the airways.1

What are the ingredients in Utibron Neohaler?

Utibron Neohaler contains indacaterol and glycopyrrolate. Indacaterol is a long-acting beta-agonist (LABA), and glycopyrrolate is a long-acting muscarinc agent (LAMA) or anticholinergic.1

How does Utibron Neohaler work?

The two medicines in Utibron Neohaler each work in different ways. The LABA, indacaterol, relaxes the muscles in the airways by targeting beta2-receptors. The anticholinergic, glycopyrrolate, relaxes the smooth muscles by targeting the muscarinic receptors. Together, the two medicines in Utibron Neohaler can help manage the symptoms of COPD.1,2

What are the possible side effects of Utibron Neohaler?

The most common side effects experienced by patients taking Utibron Neohaler in clinical trials include:

  • Headache
  • Diarrhea
  • Acid reflux
  • Sore throat
  • Runny nose
  • High blood pressure
  • Back pain1,2

Utibron Neohaler may cause serious side effects, including:

  • Sudden shortness of breath immediately after using the inhaler, which may be life-threatening
  • A dangerous increase in blood pressure
  • Fast or irregular heartbeat
  • Chest pain
  • Serious allergic reactions, which can cause swelling of the throat, tongue, lips, hives, rash, or difficulty breathing or swallowing
  • New or worsened eye problems
  • New or worsened urinary retention (difficulty urinating or painful urination)
  • Changes in blood tests, such as blood sugar or potassium1,2

Things to know about Utibron Neohaler

Utibron Neohaler should not be used for sudden symptoms. People using Utibron Neohaler should also have a short-acting inhaler for sudden symptoms.1

Utibron Neohaler should be used exactly as prescribed, and your doctor or pharmacist can explain how to use it. Utibron Neohaler shouldn’t be used more often than twice daily, and treatment with Utibron Neohaler should not be stopped suddenly unless told to by a healthcare professional.1,2

People who are allergic to any of the ingredients in Utibron Neohale, including indacaterol and glycopyrrolate, should not use Utibron Neohaler. Utibron Neohaler contains a small amount of milk proteins and the milk sugar lactose. People who have a severe milk allergy may experience an allergic reaction to Utibron Neohaler.1,2

Before starting treatment with Utibron Neohaler, patients should discuss all health conditions they have with their doctor, especially if they have any of the following:

  • Heart problems
  • High blood pressure
  • Seizures
  • Thyroid problems
  • Liver problems
  • Diabetes
  • Kidney problems
  • Eye problems like glaucoma
  • Prostate or bladder problems
  • Pregnancy, breastfeeding, or planning to become pregnant or breastfeed1,2

Before starting treatment with Utibron Neohaler, patients should talk to their doctor about all medicines (over-the-counter and prescription), vitamins, and supplements they are taking. Certain medications may interact with Utibron Neohaler and cause serious side effects. It is especially important to tell doctors about any anticholinergics or LABA medicines.1,2

Dosing information

Utibron Neohaler is to be used by inserting one capsule into the device for inhalation by mouth only, as instructed by your healthcare professional. Utibron Neohaler is usually used twice daily. Each powder capsule contains 27.5 mcg of indacaterol and 15.6 mcg glycopyrrolate.1

For more information, read the full prescribing information for Utibron Neohaler.

Written by: Emily Downward| Last reviewed: April 2018
View References
  1. Utibron Neohaler prescribing information. Available at https://www.utibron.com/Utibron-Prescribing-Information.pdf. Accessed 4/9/18.
  2. Utibron Neohaler product website. Available at https://www.utibron.com/. Accessed 4/9/18.